Cyclophosphamide induces durable molecular and clinical responses in patients with relapsed T-LGL leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006263
Abstract: T-cell large granular lymphocytic leukemia (T-LGLL) is a clonal proliferation of cytotoxic T-lymphocytes with a terminal effectory memory phenotype (CD3 1 /CD8 1 /CD5dim/CD57 1 /CD62L/CD45RA / CD45RO 2 ) that can result in severe… read more here.
Keywords: response; durable molecular; cyclophosphamide induces; leukemia ... See more keywords
Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed or refractory IDH1-mutated AML.
Sign Up to like & getrecommendations! Published in 2023 at "Blood advances"
DOI: 10.1182/bloodadvances.2022009411
Abstract: Olutasidenib (FT-2102) is a potent, selective, oral, small-molecule inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1). Overall, 153 IDH-1 inhibitor naïve patients with mIDH1R132 relapsed/refractory (R/R) acute myeloid leukemia (AML) received olutasidenib monotherapy 150 mg twice… read more here.
Keywords: induces durable; durable complete; relapsed refractory; 2102 induces ... See more keywords