PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells
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DOI: 10.1080/2162402x.2021.1906500
Abstract: ABSTRACT Only a small subset of colorectal cancer (CRC) patients benefits from immunotherapies, comprising blocking antibodies (Abs) against checkpoint receptor “programmed-cell-death-1” (PD1) and its ligand (PD-L1), because most cases lack the required mutational burden and… read more here.
Keywords: ppar induces; induces expression; cancer; tumor ... See more keywords
Saliva induces expression of antimicrobial peptides and promotes intracellular killing of bacteria in keratinocytes by epidermal growth factor receptor transactivation
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.14883
Abstract: Wounds in the oral cavity, constantly exposed to both saliva and bacteria, heal quickly without infection. Furthermore, during licking of skin wounds, saliva promotes wound healing and plays a role in keeping the wound free… read more here.
Keywords: saliva; expression antimicrobial; peptides promotes; saliva induces ... See more keywords
Candida induces the expression of IL‐36γ in human keratinocytes: implications for a pathogen‐driven exacerbation of psoriasis?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.14994
Abstract: Psoriasis and mycosis can present with a very similar clinical and histological appearance: Both diseases are characterized by red and scaly plaques with pustules of varying extent and by parakeratosis, acanthosis and subcorneal neutrophilic pustulosis.… read more here.
Keywords: exacerbation psoriasis; expression human; psoriasis; induces expression ... See more keywords
Leishmania infantum induces expression of the negative regulatory checkpoint, CTLA‐4, by human naïve CD8+ T cells
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DOI: 10.1111/pim.12659
Abstract: CD8+ T cells are important in mediating protective responses to intracellular pathogens. However, an uncontrolled response may lead to pathology. The role of CD8+ T cells in different clinical manifestations of human leishmaniasis is controversial… read more here.
Keywords: cd8; expression negative; cd8 cells; infantum induces ... See more keywords
Epstein-Barr Virus Induces Expression of the LPAM-1 Integrin in B Cells In Vitro and In Vivo
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DOI: 10.1128/jvi.01618-18
Abstract: EBV causes tumors in multiple organs, particularly in the oro- and nasopharyngeal area but also in the digestive system. This virus enters the body in the oropharynx and establishes a chronic infection in this area.… read more here.
Keywords: infection; ebv infected; integrin; induces expression ... See more keywords