Gambogenic acid induces ferroptosis in melanoma cells undergoing epithelial-to-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115110
Abstract: Melanoma is characterized by high malignancy and early onset of metastasis. Epithelial-to-mesenchymal transition (EMT) is an early event during tumor metastasis. Tumor cells that develop EMT can escape apoptosis, but they are vulnerable to ferroptosis… read more here.
Keywords: melanoma; mesenchymal transition; induces ferroptosis; melanoma cells ... See more keywords
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology"
DOI: 10.1016/j.tox.2020.152650
Abstract: The mechanisms underlying formaldehyde (FA)-induced neurotoxicity have not yet been fully clarified. Ferroptosis is a novel regulatory cell death and the Warburg effect is involved in regulating neural function. In this study, we investigated whether… read more here.
Keywords: induces ferroptosis; ht22 cells; warburg effect; effect ... See more keywords
Herpes Simplex Virus 1-Induced Ferroptosis Contributes to Viral Encephalitis
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02370-22
Abstract: Ferroptosis is a nonapoptotic form of programmed cell death that contributes to different neurological inflammatory diseases. However, whether HSV-1 induces ferroptosis in the CNS and the role of ferroptosis in viral pathogenesis remain unclear. ABSTRACT… read more here.
Keywords: induces ferroptosis; hsv infection; hsv; encephalitis ... See more keywords
Lysionotin Induces Ferroptosis to Suppress Development of Colorectal Cancer via Promoting Nrf2 Degradation
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1366957
Abstract: Extensive use of substances derived from natural sources has been documented in the treatment of colorectal cancer (CRC). Lysionotin (Lys) is a flavonoid present in the flowers and leaves of Gesneriaceae family plants. Despite its… read more here.
Keywords: induces ferroptosis; crc; colorectal cancer; treatment ... See more keywords
Individual Expression of Hepatitis A Virus 3C Protease Induces Ferroptosis in Human Cells In Vitro
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22157906
Abstract: Regulated cell death (RCD) is a fundamental process common to nearly all living beings and essential for the development and tissue homeostasis in animals and humans. A wide range of molecules can induce RCD, including… read more here.
Keywords: cell; induces ferroptosis; ferroptosis; hepatitis virus ... See more keywords
High-throughput screening identification of a small-molecule compound that induces ferroptosis and attenuates the invasion and migration of hepatocellular carcinoma cells by targeting the STAT3/GPX4 axis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Oncology"
DOI: 10.3892/ijo.2023.5490
Abstract: Hepatocellular carcinoma (HCC) is a lethal malignancy. Although considerable efforts have been made in recent years regarding treatments, effective therapeutic drugs for HCC remain insufficient. In the present study, polyphyllin VI was identified as a… read more here.
Keywords: hcc cells; gpx4; induces ferroptosis; polyphyllin ... See more keywords