A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants.
Sign Up to like & getrecommendations! Published in 2021 at "Nature microbiology"
DOI: 10.1038/s41564-021-00911-1
Abstract: The ability of gut bacterial pathogens to escape immunity by antigenic variation-particularly via changes to surface-exposed antigens-is a major barrier to immune clearance1. However, not all variants are equally fit in all environments2,3. It should… read more here.
Keywords: induces immunoglobulin; oral vaccine; vaccine induces; antigen ... See more keywords