Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis
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DOI: 10.3389/fcimb.2022.862582
Abstract: Irg1 is an enzyme that generates itaconate, a metabolite that plays a key role in the regulation of inflammatory responses. Previous studies have implicated Irg1 as an important mediator in preventing excessive inflammation and tissue… read more here.
Keywords: mycobacterium tuberculosis; bacterial phagocytosis; phagocytosis; induces irg1 ... See more keywords