Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING.
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DOI: 10.1016/j.molcel.2019.02.038
Abstract: Interleukin-1 beta (IL-1β) is a pleiotropic mediator of inflammation and is produced in response to a wide range of stimuli. During infection, IL-1β production occurs in parallel with the onset of innate antimicrobial defenses, but… read more here.
Keywords: innate; induces mtdna; cgas sting; innate immune ... See more keywords