Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells
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DOI: 10.3390/cancers14143402
Abstract: Simple Summary We exposed LUHMES cells, differentiated into mature neurons, to bortezomib (BTZ) in two treatment cycles and analyzed the methylomes of these cells after each cycle, controlling the analysis for the methylation changes potentially… read more here.
Keywords: long term; methylation changes; neuronal cells; treatment ... See more keywords
Haptoglobin Induces a Specific Proteomic Profile and a Mature-Associated Phenotype on Primary Human Monocyte-Derived Dendritic Cells
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DOI: 10.3390/ijms23136882
Abstract: Damage-associated molecular patterns (DAMPs) play a critical role in dendritic cells (DCs) ability to trigger a specific and efficient adaptive immune response for different physiological and pathological scenarios. We have previously identified constitutive DAMPs (HMGB1… read more here.
Keywords: primary human; proteomic profile; haptoglobin induces; dendritic cells ... See more keywords