Omeprazole induces vascular remodeling by mechanisms involving xanthine oxidoreductase and matrix metalloproteinase activation.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114633
Abstract: Proton pump inhibitors (PPI) are commonly used drugs that may increase the cardiovascular risk by mechanisms not entirely known. We examined whether the PPI omeprazole promotes vascular oxidative stress mediated by xanthine oxidoreductase (XOR) leading… read more here.
Keywords: induces vascular; vascular remodeling; omeprazole induces; xor ... See more keywords
Abstract 68: Soluble FMS-Like Tyrosine Kinase 1 induces Vascular Endothelial Dysfunction in Pregnant Female Mice
Sign Up to like & getrecommendations! Published in 2024 at "Hypertension"
DOI: 10.1161/hyp.81.suppl_1.68
Abstract: Preeclampsia (PE) is a hypertensive disorder of pregnancy clinically characterized by hypertension and increased risk of fetal growth restriction. Elevated levels of anti-angiogenic soluble fms-like tyrosine kinase 1 (sFlt-1) is a well-known hallmark of PE.… read more here.
Keywords: mice; vascular endothelial; endothelial dysfunction; induces vascular ... See more keywords