Omeprazole induces vascular remodeling by mechanisms involving xanthine oxidoreductase and matrix metalloproteinase activation.
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DOI: 10.1016/j.bcp.2021.114633
Abstract: Proton pump inhibitors (PPI) are commonly used drugs that may increase the cardiovascular risk by mechanisms not entirely known. We examined whether the PPI omeprazole promotes vascular oxidative stress mediated by xanthine oxidoreductase (XOR) leading… read more here.
Keywords: induces vascular; vascular remodeling; omeprazole induces; xor ... See more keywords