DiCre-Based Inducible Gene Expression.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_11
Abstract: Induction of gene expression is a valuable approach for functional studies since it allows for the assessment of phenotypes without the need for clonal selection. Inducible expression can find a wide range of applications, from… read more here.
Keywords: dicre based; gene expression; based inducible; expression ... See more keywords
A flavivirus-inducible gene expression system that modulates broad-spectrum antiviral activity against dengue and Zika viruses.
Sign Up to like & getrecommendations! Published in 2022 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2022.103723
Abstract: Incidence of dengue virus (DENV) and Zika virus (ZIKV), two mosquito-borne flaviviruses, is increasing in large parts of the world. Vaccination and medication for these diseases are unsatisfactory. Here, we developed a novel antiviral approach,… read more here.
Keywords: system; expression system; virus; gene expression ... See more keywords
HIF‐dependent and reversible nucleosome disassembly in hypoxia‐inducible gene promoters
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.03.020
Abstract: ABSTRACT Hypoxia causes dramatic changes in gene expression profiles, and the mechanism of hypoxia‐inducible transcription has been analyzed for use as a model system of stress‐inducible gene regulation. In this study, changes in chromatin organization… read more here.
Keywords: transcription; gene promoters; gene; inducible gene ... See more keywords
Suppression of p53-inducible gene 3 is significant for glioblastoma progression and predicts poor patient prognosis
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DOI: 10.1177/1010428317694572
Abstract: Glioblastoma is the most malignant and invasive brain tumor with extremely poor prognosis. p53-inducible gene 3, a downstream molecule of the tumor suppressor p53, has been found involved in apoptosis and oxidative stress response. However,… read more here.
Keywords: p53 inducible; prognosis; inducible gene; glioblastoma ... See more keywords
Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I–Mediated Antiviral Responses in Primary Human Dendritic Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.910864
Abstract: Dendritic cells (DCs) are important mediators of the induction and regulation of adaptive immune responses following microbial infection and inflammation. Sensing environmental danger signals including viruses, microbial products, or inflammatory stimuli by DCs leads to… read more here.
Keywords: primary human; retinoic acid; glycolysis; inducible gene ... See more keywords
Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.893204
Abstract: Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor that contains two CARD domains, an RNA helicase domain, and a C-terminal domain. RIG-I initiates antiviral innate immunity by recognizing exogenous viral RNAs/DNAs. However,… read more here.
Keywords: gene rig; retinoic acid; acid inducible; inducible gene ... See more keywords