The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms
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DOI: 10.1002/jlb.2mr1021-260r
Abstract: TLRs reprogram macrophage metabolism, enhancing glycolysis and promoting flux through the tricarboxylic acid cycle to enable histone acetylation and inflammatory gene expression. The histone deacetylase (HDAC) family of lysine deacetylases regulates both TLR‐inducible glycolysis and… read more here.
Keywords: histone deacetylase; murine macrophages; histone; inducible glycolysis ... See more keywords