LKB1-Salt-Inducible Kinase Signaling Is Essential in MEF2C+ Leukemia.
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DOI: 10.1158/2159-8290.cd-rw2018-044
Abstract: MEF2C activity in acute myeloid leukemia is dependent upon salt-inducible kinase (SIK) signaling. read more here.
Keywords: leukemia; inducible kinase; mef2c; salt inducible ... See more keywords
An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice
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DOI: 10.3390/ijms23147927
Abstract: Six mutations in the salt-inducible kinase 1 (SIK1) have been identified in developmental and epileptic encephalopathy (DEE-30) patients, and two of the mutations are nonsense mutations that truncate the C-terminal region of SIK1. In a… read more here.
Keywords: salt inducible; nmda induced; epileptic seizures; sik1 ... See more keywords