Development of a robust bioassay of monoclonal antibodies and biosimilars against TNF-α by NF-κB-inducible lentiviral reporter gene.
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DOI: 10.1016/j.intimp.2021.107418
Abstract: The tumor necrosis factor alpha (TNF-α)/nuclear factor-kappa B (NF-κB) signaling pathway plays a crucial role in the pathogenesis of inflammatory diseases. Several therapeutic monoclonal antibodies (mAbs) and biosimilars against TNF-α have been developed to treat… read more here.
Keywords: monoclonal antibodies; reporter gene; biosimilars tnf; inducible lentiviral ... See more keywords