13 Inducible macrolide resistance rates and erm(41) mutation profile in Mycobacterium abscessus complex isolates at a national reference laboratory
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DOI: 10.1093/ajcp/aqaf121.440
Abstract: Mycobacterium abscessus complex (MABC) is the most common rapidly growing, nontuberculous mycobacterium (NTM) that causes chronic pulmonary disease and cutaneous infections. Resistance to macrolides, a cornerstone in rapidly growing mycobacterium (RGM) treatment, is a major… read more here.
Keywords: resistance; inducible macrolide; mycobacterium; abscessus ... See more keywords
P-784. Early Prediction of Inducible Macrolide Resistance For Mycobacterium abscessus –Minimum Inhibitory Concentrations at Day 7 Versus Day 14
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DOI: 10.1093/ofid/ofae631.978
Abstract: Abstract Background Mycobacterium abscessus is notoriously difficult to treat. Current guidelines suggest a 14-day long incubation period and/or sequencing of erm41 to detect inducible macrolide resistance when treating pulmonary disease. However, the lengthy incubation is… read more here.
Keywords: macrolide; resistance; inducible macrolide; abscessus ... See more keywords
Luciferase reporter mycobacteriophage (TM4::GeNL) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in Mycobacterium abscessus complex
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DOI: 10.1128/jcm.00841-25
Abstract: ABSTRACT Mycobacterium abscessus (MAB) infections are challenging to treat due to high-level resistance to anti-tuberculosis drugs, carbapenems, fluoroquinolones, and tetracyclines. Clarithromycin and amikacin are considered cornerstone drugs for MAB treatment due to their superior efficacy;… read more here.
Keywords: resistance; inducible macrolide; susceptibility; drug ... See more keywords
Impact on Macrolide Resistance of Genetic Diversity of Mycobacterium abscessus Species
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DOI: 10.1128/spectrum.02749-22
Abstract: Macrolides are the mainstays of the antimycobacterial regimens against Mycobacterium abscessus species (formerly Mycobacterium abscessus complex). erm(41) confers inducible macrolide resistance for M. abscessus subsp. bolletii strains, and the majority of M. abscessus subsp. abscessus… read more here.
Keywords: inducible macrolide; abscessus species; macrolide resistance; abscessus subsp ... See more keywords