Inhibition of inducible nitric oxide production by Caryota urens and its active constituents umbelliferone and rutin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ayurveda and Integrative Medicine"
DOI: 10.1016/j.jaim.2020.09.002
Abstract: Inducible Nitric Oxide Synthase (iNOS) is a key mediator in a variety of diseases, and thus it is interesting to discover new iNOS inhibitors. This study aimed to evaluate if the hydroalcoholic leaf extract of… read more here.
Keywords: nitric oxide; caryota urens; oxide production; inducible nitric ... See more keywords
Altered expression of cyclooxygenase-2, 12-lipoxygenase, inducible nitric oxide synthase-2 and surfactant protein D in lungs of patients with pulmonary injury caused by sulfur mustard
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2018.1442474
Abstract: Abstract Context: Sulfur mustard (SM) is a strong alkylating toxicant that targets different organs, particularly human lung tissue. Change in genes expression is one of the molecular mechanisms of SM toxicity in damaged tissue. Objective:… read more here.
Keywords: sulfur mustard; expression cyclooxygenase; inducible nitric; expression ... See more keywords
Constitutive expression of inducible nitric oxide synthase in healthy rat urothelium?
Sign Up to like & getrecommendations! Published in 2021 at "Scandinavian journal of urology"
DOI: 10.1080/21681805.2021.1948097
Abstract: BACKGROUND Contrasting findings have been reported regarding a possible constitutive expression of inducible nitric oxide synthase (iNOS) in a normal mammalian bladder. The current study was designed to further investigate such putative iNOS expression. MATERIALS… read more here.
Keywords: inducible nitric; expression; oxide synthase; nitric oxide ... See more keywords
Fisetin Suppresses Pulmonary Inflammatory Responses through Heme Oxygenase-1 Mediated Downregulation of Inducible Nitric Oxide Synthase.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal food"
DOI: 10.1089/jmf.2020.4755
Abstract: The effects of a mixture of fisetin on cytokine-mediated pulmonary damages have not been studied, despite its known antiviral, neuroprotective, and anti-inflammatory activities. Using lipopolysaccharide (LPS)-activated human pulmonary artery endothelial cells (HPAECs), we determined the… read more here.
Keywords: inducible nitric; inflammatory; heme oxygenase; fisetin ... See more keywords
Inducible nitric oxide synthase controls experimental Strongyloides infection
Sign Up to like & getrecommendations! Published in 2018 at "Parasite Immunology"
DOI: 10.1111/pim.12576
Abstract: Infection with Strongyloides sp. induces a host immune response, predominantly the Th2 type, that is able to eliminate the parasite. However, little is known about the role of the nitric oxide (NO) mediator, induced by… read more here.
Keywords: inducible nitric; infection; mice; oxide synthase ... See more keywords
Evaluation of inducible nitric oxide synthase inhibition on kidney function and structure in high‐fat diet‐induced kidney disease
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Physiology"
DOI: 10.1113/ep086594
Abstract: What is the central question of this study? The metabolic pathways regulating the effects of obesity on the kidney remain unknown. We sought to determine whether inducible nitric oxide synthase (iNOS) is involved in the… read more here.
Keywords: kidney; induced kidney; inducible nitric; nitric oxide ... See more keywords
Preexisting Heterogeneity of Inducible Nitric Oxide Synthase Expression Drives Differential Growth of Mycobacterium tuberculosis in Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02251-22
Abstract: In this report, we demonstrate that fluctuations in the expression of antimicrobial genes can define how single host cells control bacterial infections. We show that preexisting cell-to-cell variation in the expression of a single gene,… read more here.
Keywords: cell; inducible nitric; nitric oxide; expression ... See more keywords
Osteogenic Effect of Inducible Nitric Oxide Synthase (iNOS)-Loaded Mineralized Nanoparticles on Embryonic Stem Cells
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000495330
Abstract: Background/Aims: This study investigated the effect of inducible nitric oxide synthase-loaded mineralized nanoparticles (iNOS-MNPs) on the osteogenic differentiation of mouse embryonic stem cells (ESCs). Methods: We prepared iNOS-MNPs using an anionic block copolymer template-mediated calcium… read more here.
Keywords: inducible nitric; inos mnps; osteogenic differentiation; nitric oxide ... See more keywords
Plaunol A from Croton stellatopilosus Inhibits Inducible Nitric Oxide Synthase and Cyclooxygenase-2 in Macrophage RAW264.7 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Communications"
DOI: 10.1177/1934578x1801300703
Abstract: A clerodane diterpene (plaunol A) and three flavonoids (vitexin; luteolin-7-O-β-D-glucoside and luteolin-4'-O-glucoside) were isolated from stems and leaves of Croton stellatoliosus Ohba, using series of chromatographic techniques. Evaluation for anti-inflammatory activity in LPS-induced RAW264.7 cells… read more here.
Keywords: inducible nitric; synthase cyclooxygenase; oxide synthase; nitric oxide ... See more keywords
Detection of artemisinin effect on macrophage inducible nitric oxide gene expression in macrophage infected with Leishmania donovani.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of parasitology"
DOI: 10.17420/ap6802.439
Abstract: Leishmaniosis is a parasitic infection spreads to humans by sand flies. Over 20 different species of Leishmania are responsible for the disease, which infect over 14 million people around the world. Chemotherapy is one of… read more here.
Keywords: inducible nitric; expression; leishmania donovani; gene expression ... See more keywords
Inducible Nitric Oxide Synthase iNOS-954-G>C and Ex16+14-C>T Gene Polymorphisms and Susceptibility to Vitiligo in the Saudi Population
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s344415
Abstract: Objective Vitiligo is an acquired pigmentary skin disorder with regional disappearance of melanocytes. Multigenic inheritance has been proposed in the pathogenesis of vitiligo. The present study aimed to investigate the possible association of inducible nitric… read more here.
Keywords: vitiligo saudi; inducible nitric; inos 954; nitric oxide ... See more keywords