Hormone-Inducible Transport Reporter Assay to Study Nuclear Import Defects in Neurodegenerative Diseases.
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DOI: 10.1007/978-1-0716-2337-4_5
Abstract: In the recent years, defective nuclear import has emerged as an important pathomechanism of neurodegenerative diseases, particularly in amyotrophic lateral sclerosis (ALS). Here, specific nuclear RNA binding proteins (RBPs) mislocalize and aggregate in the cytoplasm… read more here.
Keywords: import; hormone inducible; nuclear import; inducible transport ... See more keywords