Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.117
Abstract: Differentiation-inducing factor-1 (DIF-1), a morphogen produced by the cellular slime mold Dictyostelium discoideum, is a natural product that has attracted considerable attention for its antitumor properties. Here, we report a novel inhibitory effect of DIF-1… read more here.
Keywords: differentiation inducing; dif; activation; hepatic stellate ... See more keywords
Biological signalling supports biotechnology - Pulsed electric fields extract a cell-death inducing factor from Chlorella vulgaris.
Sign Up to like & getrecommendations! Published in 2021 at "Bioelectrochemistry"
DOI: 10.1016/j.bioelechem.2021.107991
Abstract: Compared to mechanical extraction methods, pulsed electric field (PEF) treatment provides an energy-efficient and gentle alternative. However, the biological processes involved are poorly understood. The unicellular green microalga Chlorella vulgaris was used as model organism… read more here.
Keywords: treatment; pef treatment; cell death; death inducing ... See more keywords
Understanding the Dr. Jekyll and Mr. Hyde nature of apoptosis-inducing factor: future perspectives
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical Journal"
DOI: 10.1016/j.bj.2017.06.004
Abstract: Apoptosis-inducing factor (AIF) is emerging as a key protein in regulation of basic physiological processes including phagocytosis, mitophagy and regulation of the redox state. Recent evidences suggest that the enzymatic activity of AIF may play… read more here.
Keywords: understanding jekyll; apoptosis inducing; inducing factor; nature ... See more keywords
Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00777
Abstract: Blocking the interaction between the apoptosis-inducing factor (AIF) and cyclophilin A (CypA) by the AIF fragment AIF(370-394) is protective against glutamate-induced neuronal cell death and brain injury in mice. Starting from AIF(370-394), we report the… read more here.
Keywords: cypa; apoptosis inducing; inducing factor; cell death ... See more keywords
The Effect of Endurance Training on Apoptotic Inducing Factor (AIF) in Cerebellum of Type 1 Diabetic Rats
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Applied Sport Science"
DOI: 10.29252/aassjournal.749
Abstract: Background. The apoptotic inducing factor (AIF) level increases in the brain of patients with diabetic disease. Objectives. This study aimed to investigate whether endurance training could alleviate apoptosis in the cerebellum of diabetic rats. Methods.… read more here.
Keywords: endurance training; cerebellum; inducing factor; factor aif ... See more keywords
Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury
Sign Up to like & getrecommendations! Published in 2021 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.290875
Abstract: Perinatal complications, such as asphyxia, can cause brain injuries that are often associated with subsequent neurological deficits, such as cerebral palsy or mental retardation. The mechanisms of perinatal brain injury are not fully understood, but… read more here.
Keywords: factor; brain injury; apoptosis inducing; inducing factor ... See more keywords