A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation.
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DOI: 10.1111/bph.16058
Abstract: BACKGROUND AND PURPOSE Chronic inflammation is pathogenic and contributes to many human diseases, positing a significant threat to the public health. The NLR family pyrin domain-containing protein 3 (NLRP3) is the best-characterized factor regulating inflammation.… read more here.
Keywords: inflammation; compound; nlrp3 protein; degradation ... See more keywords