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Published in 2019 at "Nature Methods"
DOI: 10.1038/s41592-019-0685-3
Abstract: Protein functions and cellular signaling pathways can be modulated by selectively degrading certain proteins. PROTACs, proteolysis-targeting chimeras, are molecules that recognize and bind both the protein of interest and E3 ubiquitin ligase — an enzyme…
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Keywords:
degradation;
degradation using;
using light;
protein degradation ... See more keywords
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Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11040666
Abstract: The C-Maf-Inducing protein (CMIP) was first described as overexpressed in T cell subpopulations of idiopathic nephrotic syndrome (INS) patients. Later, it was found concomitantly upregulated in podocytes. CMIP expression has also been reported in several…
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Keywords:
cancer;
maf inducing;
inducing protein;
role ... See more keywords