Effect of Induction Chemotherapy With Paclitaxel, Cisplatin, and Capecitabine vs Cisplatin and Fluorouracil on Failure-Free Survival for Patients With Stage IVA to IVB Nasopharyngeal Carcinoma: A Multicenter Phase 3 Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.0122
Abstract: Importance Induction chemotherapy added to concurrent chemoradiotherapy significantly improves survival for patients with locoregionally advanced nasopharyngeal carcinoma, but the optimal induction regimen remains unclear. Objective To determine whether induction chemotherapy with paclitaxel, cisplatin, and capecitabine… read more here.
Keywords: nasopharyngeal carcinoma; free survival; induction chemotherapy; cisplatin ... See more keywords
A dynamic 3‐factor survival model for acute myeloid leukemia that accounts for response to induction chemotherapy
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DOI: 10.1002/ajh.26630
Abstract: The current study was approached with the assumption that response to induction chemotherapy, in acute myeloid leukemia (AML), overshadows pre‐treatment risk variables in predicting survival and therefore be used as an anchor for a simplified… read more here.
Keywords: myeloid leukemia; induction chemotherapy; response induction; risk ... See more keywords
The immune modulation effects of gemcitabine plus cisplatin induction chemotherapy in nasopharyngeal carcinoma
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DOI: 10.1002/cam4.4705
Abstract: Studies are trying to add immunotherapy to gemcitabine and cisplatin (GP) induction chemotherapy, the standard therapy, in nasopharyngeal carcinoma (NPC) patients with locoregionally advanced disease. However, how the immune system responds to GP remains unknown. read more here.
Keywords: nasopharyngeal carcinoma; induction chemotherapy; immune modulation; cisplatin induction ... See more keywords
Efficacy of adjuvant chemotherapy/maintenance chemotherapy after induction chemotherapy and concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: Experiences of two centers
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DOI: 10.1002/cam4.5470
Abstract: In general, there are not many studies exploring the clinical value of adjuvant chemotherapy or maintenance chemotherapy (AC/MC) after induction chemotherapy and concurrent chemoradiotherapy (IC+CCRT+AC/MC). The purpose of this study was to establish a clinical… read more here.
Keywords: induction chemotherapy; maintenance chemotherapy; adjuvant chemotherapy; chemotherapy induction ... See more keywords
Optimizing induction chemotherapy regimens for radiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma
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DOI: 10.1002/cam4.5707
Abstract: The optimal number of cycles of induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (LANPC) remains unresolved. This study aimed to quantitatively assess the changes in gross tumor volumes (GTVs) and to select the most… read more here.
Keywords: advanced nasopharyngeal; induction chemotherapy; nasopharyngeal carcinoma; locoregionally advanced ... See more keywords
Prognostic relevance of early radiologic response to induction chemotherapy in pediatric rhabdomyosarcoma: A report from the International Society of Pediatric Oncology Malignant Mesenchymal Tumor 95 study
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DOI: 10.1002/cncr.31157
Abstract: Early response to induction chemotherapy is used in current European guidelines to evaluate the efficacy of chemotherapy and subsequently to adapt treatment in pediatric patients with rhabdomyosarcoma (RMS). However, existing literature on the prognostic value… read more here.
Keywords: response; induction chemotherapy; oncology; response induction ... See more keywords
Effects of induction chemotherapy on nutrition status in locally advanced nasopharyngeal carcinoma: a multicentre prospective study
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DOI: 10.1002/jcsm.13196
Abstract: Induction chemotherapy (IC) and concurrent chemoradiotherapy (CCRT) is the standard of care for locoregionally advanced nasopharyngeal carcinoma (LA‐NPC). This intensive treatment regimen increases acute toxicities, which could negatively impact patients' nutritional status. We conducted this… read more here.
Keywords: advanced nasopharyngeal; induction chemotherapy; nasopharyngeal carcinoma; status ... See more keywords
Statistical harmonization can improve the development of a multicenter CT based radiomic model predictive of non-response to induction chemotherapy in laryngeal cancers.
Sign Up to like & getrecommendations! Published in 2021 at "Medical physics"
DOI: 10.1002/mp.14948
Abstract: PURPOSE To develop a radiomic model predicting non-response to induction chemotherapy in laryngeal cancers, from multicenter pre-therapeutic contrast-enhanced computed tomography (CE-CT) and evaluate the benefit of features harmonization in such a context. METHODS Patients (n=104)… read more here.
Keywords: chemotherapy; response; chemotherapy laryngeal; non response ... See more keywords
Relevance of apparent diffusion coefficient features for a radiomics-based prediction of response to induction chemotherapy in sinonasal cancer.
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DOI: 10.1002/nbm.4265
Abstract: In this paper, several radiomics-based predictive models of response to induction chemotherapy (IC) in sinonasal cancers (SNCs) are built and tested. Models were built as a combination of radiomic features extracted from three types of… read more here.
Keywords: radiomics based; response; chemotherapy sinonasal; weighted images ... See more keywords
Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery for patients with locally advanced rectal cancer: a systematic review and meta-analysis
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DOI: 10.1007/s00384-020-03621-y
Abstract: Background Controversy persists about whether additional induction chemotherapy (ICT) before neoadjuvant chemoradiation (NCRT) yields improved oncological outcomes. We performed a systematic review and meta-analysis to compare ICT+ NCRT+ surgery(S) with NCRT+ S in patients with… read more here.
Keywords: review meta; ict ncrt; systematic review; ncrt ... See more keywords
The evaluation of adding induction chemotherapy to concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma: a meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-020-06218-x
Abstract: We performed a meta-analysis to compare the efficacy and safety of induction chemotherapy (IC) followed by cisplatin-based concurrent chemoradiotherapy (CCRT) versus cisplatin-based CCRT for patients with locally advanced nasopharyngeal carcinoma (LA-NPC). We systematically searched PubMed,… read more here.
Keywords: cisplatin based; induction chemotherapy; based ccrt; survival ... See more keywords