Perspective of the Induction of Liver Microsomal Cytochrome P450s by Chemical Compounds
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DOI: 10.1124/dmd.122.000891
Abstract: The concept of hepatic induction of drug-metabolizing cytochrome P450s (P450s) by xenobiotics, including therapeutic drugs, was proposed in the early 1960s. A polycyclic aromatic hydrocarbon and phenobarbital have been the two major inducers used to… read more here.
Keywords: cytochrome p450s; induction liver; p450s; perspective induction ... See more keywords