Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low–molecular weight protein tyrosine phosphatase
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DOI: 10.1091/mbc.e16-10-0716
Abstract: Osteopontin (OPN), a major marker of osteogenic differentiation, suppresses osteoblast responses to mechanical stress and cytokines, including HGF and PDGF. These OPN-induced effects are mediated through focal adhesion kinase inactivation by the induction of low–molecular… read more here.
Keywords: low molecular; focal adhesion; weight protein; adhesion kinase ... See more keywords