Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"
DOI: 10.1002/14651858.cd012751
Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: We aim to conduct a systematic review and meta-analysis of all RCTs that compare biologic drugs (TNF-α antagonists, integrin antagonists, or… read more here.
Keywords: induction; induction maintenance; biologic drugs; meta analysis ... See more keywords
Higher vs Standard Adalimumab Induction and Maintenance Dosing Regimens for Treatment of Ulcerative Colitis: SERENE UC Trial Results.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.02.033
Abstract: BACKGROUND & AIMS SERENE UC evaluated the efficacy of higher adalimumab induction and maintenance dose regimens in patients with ulcerative colitis (UC). METHODS This phase 3, double-blind, randomized trial included induction and maintenance studies, with… read more here.
Keywords: adalimumab induction; dosing regimens; week; induction maintenance ... See more keywords
Rituximab Induction and Maintenance Treatment in Patients with Scleritis and Granulomatosis with Polyangiitis (Wegener’s)
Sign Up to like & getrecommendations! Published in 2018 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2017.1327602
Abstract: ABSTRACT Aims: To evaluate the efficacy and safety of rituximab (RTX) induction and maintenance treatment for patients with scleritis and granulomatosis with polyangiitis (GPA), Wegener’s. Methods: Nine patients (12 eyes) with scleritis with GPA who… read more here.
Keywords: maintenance treatment; maintenance; treatment; treatment patients ... See more keywords
Induction and Maintenance Adjuvant Mitomycin C Topical Therapy for Upper Tract Urothelial Carcinoma: Tolerability and Intermediate Term Outcomes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of endourology"
DOI: 10.1089/end.2016.0871
Abstract: PURPOSE Endoscopic management of upper tract urothelial carcinoma (UTUC) is associated with higher recurrences, which could be reduced by application of topical therapy. Adjuvant induction Bacillus Calmette-Guerin has shown inferior outcomes for UTUC compared to… read more here.
Keywords: topical therapy; maintenance adjuvant; tolerability; induction maintenance ... See more keywords
Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity.
Sign Up to like & getrecommendations! Published in 2022 at "Cerebral cortex"
DOI: 10.1093/cercor/bhac093
Abstract: The amygdala is known to modulate hippocampal synaptic plasticity. One role could be an immediate effect of basolateral amygdala (BLA) in priming synaptic plasticity in the hippocampus. Another role could be through associative synaptic co-operation… read more here.
Keywords: synaptic plasticity; maintenance synaptic; induction maintenance; plasticity ... See more keywords
Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials
Sign Up to like & getrecommendations! Published in 2017 at "Gut"
DOI: 10.1136/gutjnl-2016-312735
Abstract: Objective Tofacitinib is an oral, small-molecule Janus kinase inhibitor that is being investigated for IBD. We evaluated the efficacy and safety of tofacitinib for induction and maintenance treatment in patients with moderate-to-severe Crohn's disease (CD).… read more here.
Keywords: tofacitinib; maintenance; twice daily; induction maintenance ... See more keywords
Publisher's Note: Temporally distinct roles of ATM and ROS in genotoxic-stress-dependent induction and maintenance of cellular senescence.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.259033
Abstract: Cells exposed to genotoxic stress induce cellular senescence through a DNA damage response (DDR) pathway regulated by ATM kinase and reactive oxygen species (ROS). Here, we show that the regulatory roles for ATM kinase and… read more here.
Keywords: cellular senescence; genotoxic stress; induction maintenance; roles atm ... See more keywords
Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001813
Abstract: The reduced sleep duration previously observed in Camk2b knockout mice revealed a role for Ca2+/calmodulin-dependent protein kinase II (CaMKII)β as a sleep-promoting kinase. However, the underlying mechanism by which CaMKIIβ supports sleep regulation is largely… read more here.
Keywords: state; induction maintenance; camkii; phosphorylation ... See more keywords
Efficacy and safety of HSK3486 for the induction and maintenance of general anesthesia in elective surgical patients: a multicenter, randomized, open-label, propofol-controlled phase 2 clinical trial.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202202_28101
Abstract: OBJECTIVE To evaluate the efficacy and safety of HSK3486 for the induction and maintenance of general anesthesia in elective surgical patients, but excluding emergency, cardiothoracic, cerebral and endoscopic sinus cases. PATIENTS AND METHODS A total… read more here.
Keywords: hsk3486; maintenance general; maintenance; propofol ... See more keywords
The Role of Mast Cells in the Induction and Maintenance of Inflammation in Selected Skin Diseases
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087021
Abstract: Under physiological conditions, skin mast cells play an important role as guardians that quickly react to stimuli that disturb homeostasis. These cells efficiently support, fight infection, and heal the injured tissue. The substances secreted by… read more here.
Keywords: mast; cells induction; mast cells; role mast ... See more keywords