Combined intravenous immunoglobulin and methylprednisolone as induction treatment in chronic inflammatory demyelinating polyneuropathy (OPTIC protocol): a prospective pilot study
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DOI: 10.1111/ene.14096
Abstract: We hypothesized that combining intravenous immunoglobulin (IVIg) and intravenous methylprednisolone (IVMP) leads to more frequent remission compared with IVIg alone while maintaining the fast efficacy of IVIg. In this uncontrolled pilot study, we evaluated remission,… read more here.
Keywords: intravenous immunoglobulin; inflammatory demyelinating; pilot study; chronic inflammatory ... See more keywords
Azacitidine to Consolidate and Deepen the Therapeutic Response Achieved by Intensive Induction Treatment in a Young Patient Affected by NPM1mut-AML Who Has Become Ineligible for High-Dose Consolidation
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DOI: 10.1159/000520205
Abstract: Acute myeloid leukemia (AML) is the most common leukemia in adults. In spite of the most recent discoveries about the molecular landscape of this disease, the treatment of elderly and unfit young patients continues to… read more here.
Keywords: intensive induction; young patient; induction treatment; npm1mut aml ... See more keywords
Multitarget therapy versus monotherapy as induction treatment for lupus nephritis: A meta-analysis of randomized controlled trials
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DOI: 10.1177/09612033221122148
Abstract: Aim The safety of multitarget treatments is of concern. This study aimed to evaluate the effectiveness and safety of multitarget therapy as an induction treatment for lupus nephritis in comparison with monotherapy. Methods This study… read more here.
Keywords: mmf; group; monotherapy; induction treatment ... See more keywords
The efficacy of induction treatment in Thai patients with lupus nephritis: Observational cohort analysis
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DOI: 10.1177/09612033221149874
Abstract: Background For active proliferative lupus nephritis (LN), intravenous cyclophosphamide (IVCYC) is a standard therapy whereby mycophenolate mofetil (MMF) is less effective than IVCYC, according to the clinical trials in non-Asians. In this observational study, the… read more here.
Keywords: lupus nephritis; value; induction treatment; treatment ... See more keywords
LIS1, a glyco-humanized swine polyclonal anti-lymphocyte globulin, as a novel induction treatment in solid organ transplantation
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DOI: 10.3389/fimmu.2023.1137629
Abstract: Anti-thymocyte/lymphocyte globulins (ATGs/ALGs) are immunosuppressive drugs used in induction therapies to prevent acute rejection in solid organ transplantation. Because of animal origin, ATGs/ALGs contain highly immunogenic carbohydrate xenoantigens eliciting antibodies that are associated with subclinical… read more here.
Keywords: organ transplantation; lymphocyte; transplantation; induction treatment ... See more keywords