Performing in spite of starvation: How Saccharomyces cerevisiae maintains robust growth when facing famine zones in industrial bioreactors
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DOI: 10.1111/1751-7915.14188
Abstract: In fed‐batch operated industrial bioreactors, glucose‐limited feeding is commonly applied for optimal control of cell growth and product formation. Still, microbial cells such as yeasts and bacteria are frequently exposed to glucose starvation conditions in… read more here.
Keywords: growth; spite starvation; starvation; industrial bioreactors ... See more keywords
Mimicked Mixing-Induced Heterogeneities of Industrial Bioreactors Stimulate Long-Lasting Adaption Programs in Ethanol-Producing Yeasts
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DOI: 10.3390/genes14050997
Abstract: Commercial-scale bioreactors create an unnatural environment for microbes from an evolutionary point of view. Mixing insufficiencies expose individual cells to fluctuating nutrient concentrations on a second-to-minute scale while transcriptional and translational capacities limit the microbial… read more here.
Keywords: scale; heterogeneities industrial; mixing induced; industrial bioreactors ... See more keywords