Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy
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DOI: 10.1101/mcs.a006220
Abstract: Infants diagnosed with acute myeloid leukemia (AML) frequently harbor cytogenetically cryptic fusions involving KMT2A, NUP98, or GLIS2. Those with AML driven specifically by CBFA2T3::GLIS2 fusions have a dismal prognosis and are currently risk-stratified to receive… read more here.
Keywords: fusion; infant aml; glis3; aml refractory ... See more keywords