Effect of General Anesthesia and Conscious Sedation During Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke: A Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.4474
Abstract: Importance Endovascular therapy (EVT) is the standard of care for select patients who had a stroke caused by a large vessel occlusion in the anterior circulation, but there is uncertainty regarding the optimal anesthetic approach… read more here.
Keywords: ischemic stroke; trial; clinical outcomes; infarct growth ... See more keywords
Mediation of Successful Reperfusion Effect through Infarct Growth and Cerebral Edema: A Pooled, Patient‐Level Analysis of EXTEND‐IA Trials and SELECT Prospective Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26587
Abstract: Reperfusion therapy is highly beneficial for ischemic stroke. Reduction in both infarct growth and edema are plausible mediators of clinical benefit with reperfusion. We aimed to quantify these mediators and their interrelationship. read more here.
Keywords: mediation successful; reperfusion; infarct growth; successful reperfusion ... See more keywords
Hypoperfusion Intensity Ratio Predicts Infarct Growth After Successful Thrombectomy for Distal Medium Vessel Occlusion
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-022-01141-6
Abstract: This study evaluated whether quantitative measurement of collaterals by the hypoperfusion intensity ratio (HIR) on baseline computed tomography perfusion (CTP) correlated with infarct growth and clinical outcome after successful endovascular recanalization of acute ischemic stroke… read more here.
Keywords: growth successful; analysis; intensity ratio; growth ... See more keywords
Infarct growth patterns may vary in acute stroke due to large vessel occlusion and recanalization with endovascular therapy
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-07068-1
Abstract: This study aimed to investigate infarct growth patterns in stroke patients with large vessel occlusion (LVO) and successful recanalization by endovascular therapy (EVT). A total of 135 patients with LVO of the internal carotid artery… read more here.
Keywords: growth; infarct growth; pattern models; growth patterns ... See more keywords
Impact of varying levels of hyperglycemia on clinicoradiographic outcomes after endovascular reperfusion treatment
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28175-6
Abstract: We evaluated the effects of admission hyperglycemia with different cut-off levels on 3-month outcomes, infarct growth, and hemorrhagic transformation in acute stroke patients with large artery occlusion of anterior circulation who received endovascular treatment (EVT).… read more here.
Keywords: moderate hyperglycemia; poor outcomes; infarct growth; treatment ... See more keywords
Is infarct core growth linear? Infarct volume estimation by computed tomography perfusion imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Acta neurologica Scandinavica"
DOI: 10.1111/ane.13601
Abstract: OBJECTIVES Current guidelines for recanalization treatment are based on the time elapsed between symptom onset and treatment and visualization of existing penumbra in computed tomography perfusion (CTP) imaging. The time window for treatment options relies… read more here.
Keywords: time; growth linear; growth; volume ... See more keywords
Collateral Clock Is More Important Than Time Clock for Tissue Fate: A Natural History Study of Acute Ischemic Strokes
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/strokeaha.118.021484
Abstract: Background and Purpose— Although perfusion abnormality is an increasingly important therapeutic target, the natural history of tissue at risk without reperfusion treatment is understudied. Our objective was to determine how time affects penumbral salvage and… read more here.
Keywords: penumbral salvage; salvage infarct; infarct growth; time ... See more keywords
Bridge to Arrest Infarct Growth
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000207383
Abstract: Intravenous thrombolysis (IVT) has been the pillar of acute ischemic stroke therapy since the NINDS trial in 1995,1 yet IVT alone recanalizes less than 25% of large-vessel occlusion (LVO) stroke. Two decades later, 8 pivotal… read more here.
Keywords: arrest infarct; infarct growth; neurology; ivt ... See more keywords
Acute insular infarction: Early outcomes of minor stroke with proximal artery occlusion
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DOI: 10.1371/journal.pone.0229836
Abstract: Background and purpose We hypothesized that admission insular infarcts could be associated with early neurological deterioration (END) in acute minor stroke with large vessel occlusion. Methods Using acute and follow-up diffusion-weighted imaging (DWI), we assessed… read more here.
Keywords: insular lesions; infarct growth; piri scores; minor stroke ... See more keywords
Impact of Pial Collaterals on Infarct Growth Rate in Experimental Acute Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a5003
Abstract: BACKGROUND AND PURPOSE: Cerebral infarction evolves at different rates depending on available blood flow suggesting that treatment time windows vary depending on the degree of pial collateral recruitment. This work sought to mathematically model infarct… read more here.
Keywords: average pial; infarct growth; time; growth ... See more keywords