Photosensitive and Conductive Hydrogel Induced Innerved Bone Regeneration for Infected Bone Defect Repair
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201349
Abstract: Repairing infected bone defects is a challenge in the field of orthopedics because of the limited self‐healing capacity of bone tissue and the susceptibility of refractory materials to bacterial activity. Innervation is the initiating factor… read more here.
Keywords: conductive hydrogel; bone; bone regeneration; infected bone ... See more keywords
Zinc-based Tannin-modified Composite Microparticulate Scaffolds with Balanced Antimicrobial Activity and Osteogenesis for Infected Bone Defect Repair.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300303
Abstract: Treatment of infected bone defects is a major clinical challenge, bioactive materials combining sufficient antimicrobial activity and favorable osteogenic ability are urgently needed. In this study, through a facile one-pot hydrothermal reaction of zinc acetate… read more here.
Keywords: bone; activity; bone defect; infected bone ... See more keywords
Transcriptome sequencing profiling identifies miRNA-331-3p as an osteoblast-specific miRNA in infected bone nonunion.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115619
Abstract: Bone nonunion caused by bacterial infection accounts for bone fractures, bone trauma and bone transplantation surgeries. Severe consequences include delayed unions and amputation and result in functional limitations, work disability, and poor quality of life.… read more here.
Keywords: infected bone; bone nonunion; mirna 331;
Self-Adaptive Antibacterial Scaffold with Programmed Delivery of Osteogenic Peptide and Lysozyme for Infected Bone Defect Treatment.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c19026
Abstract: Bone defects caused by disease or trauma are often accompanied by infection, which severely disrupts the normal function of bone tissue at the defect site. Biomaterials that can simultaneously reduce inflammation and promote osteogenesis are… read more here.
Keywords: lysozyme; bone; scaffold; infected bone ... See more keywords
3D-printed composite scaffold with anti-infection and osteogenesis potential against infected bone defects
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DOI: 10.1039/d2ra00214k
Abstract: In the field of orthopedics, an infected bone defect is a refractory disease accompanied by bone infection and defects as well as aggravated circulation. There are currently no personalized scaffolds that can treat bone infections… read more here.
Keywords: infected bone; infection; bone defects; plla pearl ... See more keywords
β-tricalcium phosphate/gelatin composite scaffolds incorporated with gentamycin-loaded chitosan microspheres for infected bone defect treatment
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277522
Abstract: The repair of infected bone defects remains a clinical challenge. Staphylococcus aureus is a common pathogenic micro-organism associated with such infections. Gentamycin (GM) is a broad spectrum antibiotic that can kill S. aureus in a… read more here.
Keywords: bone; composite scaffolds; release; infected bone ... See more keywords
The Antibacterial Effect, Biocompatibility, and Osteogenesis of Vancomycin-Nanodiamond Composite Scaffold for Infected Bone Defects
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s397316
Abstract: Purpose The repair and treatment of infected bone defects (IBD) is a common challenge faced by orthopedic clinics, medical materials science, and tissue engineering. Methods Based on the treatment requirements of IBD, we utilized multidisciplinary… read more here.
Keywords: biocompatibility osteogenesis; effect; biocompatibility; scaffold ... See more keywords
Chitosan-Based Biomaterial Scaffolds for the Repair of Infected Bone Defects
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.899760
Abstract: The treatment of infected bone defects includes infection control and repair of the bone defect. The development of biomaterials with anti-infection and osteogenic ability provides a promising strategy for the repair of infected bone defects.… read more here.
Keywords: chitosan based; bone; treatment infected; bone defects ... See more keywords