Development of a Microenvironment-Responsive Hydrogel Promoting Chronically Infected Diabetic Wound Healing through Sequential Hemostatic, Antibacterial, and Angiogenic Activities.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c02725
Abstract: Microenvironment-responsive hydrogels present high potential in treating refractory wounds due to their capability of on-demand drug release. In this study, a specially designed hydrogel with smart targeting of refractory wound characteristics was designed to treat… read more here.
Keywords: microenvironment responsive; sequential hemostatic; chronically infected; antibacterial angiogenic ... See more keywords
Preparation of Photocatalytic and Antibacterial MOF Nanozyme Used for Infected Diabetic Wound Healing.
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DOI: 10.1021/acsami.2c03001
Abstract: Bacterial infection has been a considerable obstacle for diabetic wound healing. A multifunctional nanoplatform used as nanozyme for bacterial infected diabetic wound is extremely attractive. Therefore, gold nanoclusters modified zirconium-based porphyrin metal-organic frameworks (Au NCs@PCN)… read more here.
Keywords: infected diabetic; diabetic wound; wound healing; ncs pcn ... See more keywords
Bioactive Injectable Hydrogel Dressings for Bacteria-Infected Diabetic Wound Healing: A "Pull-Push" Approach.
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DOI: 10.1021/acsami.2c04300
Abstract: Chronic diabetic wound healing remains a challenge due to the existence of excessive danger molecules and bacteria in the inflammatory microenvironment. There is an urgent need for advanced wound dressings that target both inflammation and… read more here.
Keywords: wound healing; hydrogel; infected diabetic; diabetic wound ... See more keywords
Infected Diabetic Wound Regeneration Using Peptide-Modified Chiral Dressing to Target Revascularization.
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DOI: 10.1021/acsnano.2c10039
Abstract: Revascularization plays a critical role in the healing of diabetic wounds. Accumulation of advanced glycation end products (AGEs) and refractory multidrug resistant bacterial infection are the two major barriers to revascularization, directly leading to impaired… read more here.
Keywords: wound; target revascularization; infected diabetic; diabetic wound ... See more keywords
Sonocatalytic hydrogen/hole-combined therapy for anti-biofilm and infected diabetic wound healing
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DOI: 10.1093/nsr/nwad063
Abstract: ABSTRACT It is a great challenge to effectively eradicate biofilm and cure biofilm-infected diseases because dense extracellular polymeric substance matrix prevents routine antibacterial agents from penetrating into biofilm. H2 is an emerging energy-regulating molecule possessing… read more here.
Keywords: hole; hydrogen; infected diabetic; diabetic wound ... See more keywords
Nanofiber-mediated sequential photothermal antibacteria and macrophage polarization for healing MRSA-infected diabetic wounds
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DOI: 10.1186/s12951-021-01152-4
Abstract: Background Diabetic wound healing remains a challenge because of its susceptibility to drug-resistant bacterial infection and its persistent proinflammatory state. Switching from proinflammatory M1 macrophages (Mφs) to proregenerative M2 dominant Mφs in a timely manner… read more here.
Keywords: mrsa infected; infected diabetic; polarization; diabetic wounds ... See more keywords
Microbiome Characterization of Infected Diabetic Foot Ulcers in Association With Clinical Outcomes: Traditional Cultures Versus Molecular Sequencing Methods
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.836699
Abstract: Background Infected diabetic foot ulcers (IDFU) are a major complication of diabetes mellitus. These potentially limb-threatening ulcers are challenging to treat due to impaired wound healing characterizing diabetic patients and the complex microbial environment of… read more here.
Keywords: clinical outcomes; diabetic foot; association clinical; foot ulcers ... See more keywords