Evidence for the involvement of interleukin-1α during development of experimental cytomegalovirus retinitis in immunosuppressed mice.
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DOI: 10.1016/j.cyto.2021.155596
Abstract: Interleukin-1α (IL-1α) is an alarmin involved in the recruitment of macrophages and neutrophils during tissue inflammation. IL-1α can undergo cleavage by proteases, such as calpain-1, that enhances IL-1α binding to its receptor, although proteolytic cleavage… read more here.
Keywords: mcmv infected; retinitis; mice; development ... See more keywords