Susceptibility to mice and potential evolutionary characteristics of porcine deltacoronavirus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28048
Abstract: Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in suckling piglets and has the potential for cross‐species transmission, posing a threat to animal and human health. However, the susceptibility profile of different species… read more here.
Keywords: evolutionary characteristics; infected mice; porcine deltacoronavirus; susceptibility ... See more keywords
Molecular docking to Toxoplasma gondii thymidylate synthase-dihydrofolate reductase and efficacy of raltitrexed in infected mice
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology Research"
DOI: 10.1007/s00436-018-5835-5
Abstract: Toxoplasmosis is a zoonosis of worldwide distribution. Currently, two drugs, pyrimethamine and sulfadiazine, are used as a reference in the treatment of toxoplasmosis, but the resistance of Toxoplasma gondii appears as a relevant public health… read more here.
Keywords: gondii thymidylate; gondii; thymidylate synthase; infected mice ... See more keywords
Entecavir Therapy Reverses Gut Microbiota Dysbiosis Induced by Hepatitis B Virus Infection in a Mouse Model.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2020.106000
Abstract: Chronic hepatitis B virus (HBV) infection is a global public health problem. The gut microbiota has been linked to pathogenesis of liver diseases induced by chronic HBV infection. In this study, a recombinant adeno-associated virus… read more here.
Keywords: hbv infected; infection; hbv; infected mice ... See more keywords
Andrographolide sulfonate reduces mortality in Enterovirus 71 infected mice by modulating immunity
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.11.042
Abstract: ABSTRACT Outbreaks of hand, foot and mouth disease (HFMD), which is caused by Enterovirus 71 (EV71), have erupted in recent years. Andrographolide sulfonate (Trade name: Xiyanping injection) has been recommended to treat severe HFMD in… read more here.
Keywords: immunity; andrographolide sulfonate; infected mice; mice ... See more keywords
Melatonin mediated Foxp3‐downregulation decreases cytokines production via the TLR2 and TLR4 pathways in H. pylori infected mice
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.08.034
Abstract: ABSTRACT Melatonin has important immuno‐regulatory effects in inflammatory disorders but its specific role in Helicobacter pylori induced gastritis remains unclear. The aim of our study was to analyze the activity of melatonin against H. pylori… read more here.
Keywords: tlr2; treatment; infected mice; mice ... See more keywords
Indigofera oblongifolia protects against trypanosomiasis-induced spleen injury.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of infection and public health"
DOI: 10.1016/j.jiph.2019.03.005
Abstract: BACKGROUND Trypanosomiasis is a neglected tropical disease, transmitted by blood-sucking insects and can affect humans and animals, depending on the species of Trypanosoma parasite. Trypanosoma has acquired resistance to the majority of drugs used; hence,… read more here.
Keywords: evansi infected; infected mice; ioe; evansi ... See more keywords
Combination drug treatment prolongs survival of experimentally infected mice with silver-haired bat rabies virus.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.065
Abstract: Rabies is a lethal disease in humans and animals, killing approximately 60,000 people every year. Currently, there is no treatment available, except post-exposure prophylaxis (PEP) that can be administered whenever exposure to a rabid animal… read more here.
Keywords: rabies virus; drug treatment; treatment; infected mice ... See more keywords
Assessment of the antigenic and neuroprotective activity of the subunit anti-Toxoplasma vaccine in T. gondii experimentally infected mice.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2018.02.043
Abstract: The aim of this study was to evaluate the immunogenic and immunoprotective activities and to determine the neuroprotective capacity of the tetravalent vaccine containing selected recombinant T. gondii antigens (ROP2 + ROP4 + SAG1 + MAG1) administered with safe adjuvants (MPL… read more here.
Keywords: gondii; infected mice; vaccine; antigenic neuroprotective ... See more keywords
Exploration of the mechanisms of Ge Gen Decoction against influenza A virus infection
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Journal of Natural Medicines"
DOI: 10.1016/s1875-5364(19)30079-2
Abstract: Abstract Ge Gen Decoction (GGD), a Traditional Chinese Medicine prescription, is mainly used to treat infectious respiratory diseases and can relieve the symptoms of influenza A virus (IAV) infection. However, the underlying mechanism of GGD… read more here.
Keywords: infected mice; h1n1 infected; gen decoction; infection ... See more keywords
High Dose and Delayed Treatment with Bile Acids Ineffective in RML Prion-Infected Mice
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00222-18
Abstract: ABSTRACT Prion diseases are a group of neurodegenerative diseases associated with the misfolding of the cellular prion protein (PrPC) into the infectious form (PrPSc). There are currently no treatments for prion disease. Bile acids have… read more here.
Keywords: bile acids; high dose; treatment; prion ... See more keywords
Cystatins 9 and C as a Novel Immunotherapy Treatment That Protects against Multidrug-Resistant New Delhi Metallo-Beta-Lactamase-1-Producing Klebsiella pneumoniae
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01900-17
Abstract: ABSTRACT Multidrug-resistant (MDR) bacterial pneumonia can induce dysregulated pulmonary and systemic inflammation leading to morbidity and mortality. Antibiotics to treat MDR pathogens do not function to modulate the extent and intensity of inflammation and can… read more here.
Keywords: new delhi; treatment; pneumoniae; infected mice ... See more keywords