Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques
Sign Up to like & getrecommendations! Published in 2020 at "Cell Reports"
DOI: 10.1016/j.celrep.2020.108122
Abstract: Summary BG505 SOSIP is a well-characterized near-native recombinant HIV Envelope (Env) trimer that holds promise as part of a sequential HIV immunogen regimen to induce broadly neutralizing antibodies (bnAbs). Rhesus macaques are considered the most… read more here.
Keywords: env trimer; rhesus; antibody; rhesus macaques ... See more keywords
Mucosal T follicular helper cells in SIV-infected rhesus macaques: contributing role of IL-27
Sign Up to like & getrecommendations! Published in 2019 at "Mucosal Immunology"
DOI: 10.1038/s41385-019-0174-0
Abstract: Mesenteric lymph nodes (MLNs), that drain the large and small intestine, are critical sites for the induction of oral tolerance. Although depletion of CD4 T cells in the intestinal lamina propria is a hallmark of… read more here.
Keywords: tfh cells; rhesus macaques; helper cells; follicular helper ... See more keywords
A PEG40 Modified Peptide with High Therapeutic Efficacy in SHIV Acute Infected Rhesus Monkeys.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of virology"
DOI: 10.1128/jvi.00386-20
Abstract: Anti-human immunodeficiency virus (HIV)-1 fusion peptides have been studied for nearly two decades but few candidates have found useful clinical applications. One reason underlying the failure of such agents to reach the clinic is their… read more here.
Keywords: hiv; efficacy; rhesus monkeys; infected rhesus ... See more keywords
Effects of Early Antiretroviral Therapy on the Composition and Diversity of the Fecal Microbiome of SIV-infected Rhesus Macaques (Macaca mulatta).
Sign Up to like & getrecommendations! Published in 2022 at "Comparative medicine"
DOI: 10.30802/aalas-cm-22-000020
Abstract: HIV-infected people develop reproducible disruptions in their gastrointestinal microbiota. Despite the suppression ofHIV viremia via long-term antiretroviral therapy (ART), alterations still occur in gut microbial diversity and the commensal microbiota. Mounting evidence suggests these microbial… read more here.
Keywords: infected rhesus; antiretroviral therapy; infection; diversity ... See more keywords