Variation in ERAP2 has opposing effects on severe respiratory infection and autoimmune disease
Sign Up to like & getrecommendations! Published in 2022 at "American journal of human genetics"
DOI: 10.1101/2022.11.04.22281942
Abstract: Introduction: ERAP2 is an aminopeptidase involved in immunological antigen presentation. Genotype data in human samples from before and after the Black Death, an epidemic due to Yersinia pestis, have marked changes in population allele frequency… read more here.
Keywords: infection autoimmune; disease; respiratory infection; infection ... See more keywords
Hippo Kinases MST1/2 Regulate Immune Cell Functions in Cancer, Infection, and Autoimmune Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2020035775
Abstract: Mammalian STE20-like protein kinases (MST), including MST1, MST2, MST3, and MST4, belong to the germinal center kinase (GCK) family. Kinase MST1/2 is an important component of the Hippo pathway in regulating cell proliferation, tissue homeostasis,… read more here.
Keywords: immune; kinases mst1; hippo kinases; autoimmune diseases ... See more keywords
Helicobacter pylori Infection and Autoimmune Thyroid Diseases: The Role of Virulent Strains
Sign Up to like & getrecommendations! Published in 2019 at "Antibiotics"
DOI: 10.3390/antibiotics9010012
Abstract: Aim: To verify a possible association between overall H. pylori and CagA+ H. pylori infection and autoimmune thyroid diseases (AITDs). Methods: Consecutive patients with AITDs admitted to one single centre of Endocrinology during one solar… read more here.
Keywords: caga; infection; infection autoimmune; pylori infection ... See more keywords