Cassia auriculata and its role in infection / inflammation: A close look on future drug discovery
Sign Up to like & getrecommendations! Published in 2022 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.132345
Abstract: Abstract The herbal plants contain various active compounds which have the ability to treat several human diseases without any side effects like cancer chemotherapeutic drugs used currently. It is reported that majority of the presently… read more here.
Keywords: role infection; plant; cassia auriculata; auriculata role ... See more keywords
Infection and Inflammation Imaging: Beyond FDG.
Sign Up to like & getrecommendations! Published in 2020 at "PET clinics"
DOI: 10.1016/j.cpet.2019.11.004
Abstract: This review discusses nuclear imaging of inflammation using molecular probes beyond fluoro-d-glucose, is structured by cellular targets, and focuses on those tracers that have been successfully applied clinically. read more here.
Keywords: imaging beyond; inflammation; beyond fdg; infection inflammation ... See more keywords
Macrophage polarization in response to epigenetic modifiers during infection and inflammation.
Sign Up to like & getrecommendations! Published in 2017 at "Drug discovery today"
DOI: 10.1016/j.drudis.2016.08.006
Abstract: Macrophages are a heterogeneous population of phagocytic cells present in all tissues. Recently, several drugs that target the epigenetic machinery have emerged as attractive molecules for treating infection and inflammation by modulating macrophages. Treatment of… read more here.
Keywords: polarization response; macrophage polarization; infection inflammation; response epigenetic ... See more keywords
Emerging Principles in Myelopoiesis at Homeostasis and during Infection and Inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "Immunity"
DOI: 10.1016/j.immuni.2019.01.019
Abstract: Myelopoiesis ensures the steady state of the myeloid cell compartment. Technological advances in fate mapping and genetic engineering, as well as the advent of single cell RNA-sequencing, have highlighted the heterogeneity of the hematopoietic system… read more here.
Keywords: myelopoiesis homeostasis; inflammation; principles myelopoiesis; cell ... See more keywords
99mTc-radiolabeled Levofloxacin and micelles as infection and inflammation imaging agents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101571
Abstract: Abstract Easy and early detection of infection and inflammation is essential for early and effective treatment. In this study, PEGylated micelles were designed and both micelles and Levofloxacin were radiolabeled with 99mTcO4 - to develop… read more here.
Keywords: 99mtc micelles; inflammation; micelles infection; radiolabeling efficiency ... See more keywords
Infection and inflammation in schizophrenia and bipolar disorder
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Research"
DOI: 10.1016/j.neures.2016.11.002
Abstract: The present study investigated the relationship between exposure to infectious agents and inflammation markers in individuals with schizophrenia (SZ), bipolar disorder (BP), and controls without a psychiatric disorder. We measured plasma levels of antibodies and… read more here.
Keywords: disorder; inflammation schizophrenia; bipolar disorder; schizophrenia bipolar ... See more keywords
Hybrid PET/MRI in Infection and Inflammation: An Update About the Latest Available Literature Evidence.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in nuclear medicine"
DOI: 10.1053/j.semnuclmed.2022.10.005
Abstract: PET/MRI has been reported to be promising in the diagnosis and evaluation of infection and inflammation including brain disorders, bone and soft tissue infections and inflammations, cardiovascular, abdominal, and systemic diseases. However, evidence came out… read more here.
Keywords: pet mri; mri; infection inflammation;
Role of oxidative stress, infection and inflammation in male infertility
Sign Up to like & getrecommendations! Published in 2018 at "Andrologia"
DOI: 10.1111/and.13126
Abstract: Oxidative stress (OS), defined as an overabundance of reactive oxygen species (ROS) or a deficiency of antioxidants, has been linked to sperm damage and male infertility. There are many sources of OS and inflammation including… read more here.
Keywords: oxidative stress; infertility; infection inflammation; male infertility ... See more keywords
Simultaneous control of infection and inflammation with keratin-derived antibacterial peptides targeting TLRs and co-receptors
Sign Up to like & getrecommendations! Published in 2023 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.ade2909
Abstract: Controlling infection-driven inflammation is a major clinical dilemma because of limited therapeutic options and possible adverse effects on microbial clearance. Compounding this difficulty is the continued emergence of drug-resistant bacteria, where experimental strategies aiming to… read more here.
Keywords: inflammation; keratin derived; infection; antimicrobial peptides ... See more keywords
Infection and Inflammation MUC up the Cystic Fibrosis Airway
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2022-0182ed
Abstract: The predominant feature of cystic fibrosis (CF) is muco-obstructive lung disease. Loss of or deficiency of cystic fibrosis transmembrane receptor (CFTR) activity results in decreased chloride and bicarbonate secretion and increased apical cell membrane sodium… read more here.
Keywords: infection inflammation; airway; inflammation; cystic fibrosis ... See more keywords
Lectin-Glycan Interactions in Corneal Infection and Inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02338
Abstract: The cornea is an extraordinary component of vision that functions as the principal barrier to pathogens in the eye while allowing light transmission into the retina. Understanding the cellular and molecular mechanisms that maintain homeostasis… read more here.
Keywords: lectin glycan; interactions corneal; corneal infection; infection ... See more keywords