Inference of cancer mechanisms through computational systems analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c6mb00672h
Abstract: Large amounts of metabolomics data have been accumulated to study metabolic alterations in cancer that allow cancer cells to synthesize molecular materials necessary for cell growth and proliferation. Although metabolic reprogramming in cancer was discovered… read more here.
Keywords: metabolomics data; analysis; method; inference cancer ... See more keywords
Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-0682
Abstract: The development of a computational approach that enables accurate and robust ancestry inference from cancer-derived molecular profiles without matching cancer-free data provides a valuable methodology for genetic ancestry–oriented cancer research. read more here.
Keywords: ancestry inference; ancestry; derived molecular; inference cancer ... See more keywords
CaMeRe: A Novel Tool for Inference of Cancer Metabolic Reprogramming
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.00207
Abstract: Metabolic reprogramming is prevalent in cancer, largely due to its altered chemical environments such as the distinct intracellular concentrations of O2, H2O2 and H+, compared to those in normal tissue cells. The reprogrammed metabolisms are… read more here.
Keywords: cancer metabolic; metabolic reprogramming; tool; inference cancer ... See more keywords