Causal Inference of Genetic Variants and Genes in Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.917142
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal progressive multisystem disorder with limited therapeutic options. Although genome-wide association studies (GWASs) have revealed multiple ALS susceptibility loci, the exact identities of causal variants, genes, cell types, tissues,… read more here.
Keywords: causal inference; lateral sclerosis; inference genetic; variants genes ... See more keywords
Robust Inference of Genetic Exchange Communities from Microbial Genomes Using TF-IDF
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.00021
Abstract: Bacteria and archaea can exchange genetic material across lineages through processes of lateral genetic transfer (LGT). Collectively, these exchange relationships can be modeled as a network and analyzed using concepts from graph theory. In particular,… read more here.
Keywords: communities microbial; exchange communities; genetic exchange; robust inference ... See more keywords