Conversion of non-inferiority margin from hazard ratio to restricted mean survival time difference using data from multiple historical trials
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DOI: 10.1177/09622802221102621
Abstract: The restricted mean survival time measure has gained a lot of interests for designing and analyzing oncology trials with time-to-event endpoints due to its intuitive clinical interpretation and potentially high statistical power. In the non-inferiority… read more here.
Keywords: inferiority; time; inferiority margin; conversion ... See more keywords