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Infigratinib (BGJ398): an investigational agent for the treatment of FGFR-altered intrahepatic cholangiocarcinoma

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Published in 2020 at "Expert Opinion on Investigational Drugs"

DOI: 10.1080/13543784.2021.1864320

Abstract: ABSTRACT Introduction The fibroblast growth factor receptor (FGFR) pathway is essential in cell proliferation, differentiation, migration, and survival. Cancers such as intrahepatic cholangiocarcinoma (IHCA) have demonstrated alterations of FGFR allowing unregulated growth. Infigratinib (BGJ398) is… read more here.

Keywords: agent treatment; fgfr; treatment; intrahepatic cholangiocarcinoma ... See more keywords