Diacerein-induced interleukin-1β deficiency reduces the inflammatory infiltrate and immunoexpression of matrix metalloproteinase-8 in periodontitis in rat molars.
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DOI: 10.1002/jper.21-0375
Abstract: BACKGROUND Periodontitis (P) is an immunoinflammatory disease that involves the release of cytokines and enzymes, including interleukin-1 (IL-1) and matrix metalloproteinases (MMPs). Diacerein is an anti-IL-1 drug used for the treatment of osteoarthritis. The aim… read more here.
Keywords: infiltrate immunoexpression; collagen content; immunoexpression; rat molars ... See more keywords