Peripheral and tumor‐infiltrating immune cells are correlated with patient outcomes in ovarian cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5590
Abstract: At present, there is still a lack of reliable biomarkers for ovarian cancer (OC) to guide prognosis prediction and accurately evaluate the dominant population of immunotherapy. In recent years, the relationship between peripheral blood markers… read more here.
Keywords: tumor infiltrating; ovarian cancer; peripheral tumor; immune cells ... See more keywords
Comprehensive analyses of the heterogeneity and prognostic significance of tumor-infiltrating immune cells in non-small-cell lung cancer: Development and validation of an individualized prognostic model.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106744
Abstract: Understanding the role of tumor-infiltrating immune cells (TIICs) in non-small cell lung cancer (NSCLC) is critical to finding new prognostic biomarkers and improving prognostic evaluation. Herein, we aimed to comprehensively analyze tumor-infiltrating pattern of TIICs… read more here.
Keywords: heterogeneity; tumor infiltrating; model; infiltrating immune ... See more keywords
Regulation and characterization of tumor-infiltrating immune cells in breast cancer.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107167
Abstract: The effect of immunosuppression blockade therapies depends on the infiltration of effector T cells and other immune cells in tumor. However, it is unclear how molecular pathways regulate the infiltration of immune cells, as well… read more here.
Keywords: tumor infiltrating; infiltrating immune; cancer; immune cells ... See more keywords
Targeting Aggressive Fibroblasts to Enhance the Treatment of Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2021.1857727
Abstract: ABSTRACT Introduction Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant cancer entities, which is characterized by abundant desmoplastic stroma. The stroma consists of extracellular matrix, infiltrating immune cells, cancer-associated fibroblasts (CAFs) and others.… read more here.
Keywords: pdac; cafs; anti; stroma ... See more keywords
Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac386
Abstract: Long noncoding ribonucleic acids (RNAs; lncRNAs) have been associated with cancer immunity regulation. However, the roles of immune cell-specific lncRNAs in glioblastoma (GBM) remain largely unknown. In this study, a novel computational framework was constructed… read more here.
Keywords: cell; tumor infiltrating; immune cell; tiiclnc signature ... See more keywords
Multidimensional profiling depicts infiltrating immune cell heterogeneity in the tumor microenvironment of stage IA non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14329
Abstract: Emerging evidence has underscored infiltrating immune cells in the tumor microenvironment (TME) of non‐small cell lung cancer (NSCLC). Owing to screening programs, the prevalence of early‐stage NSCLC is growing, but its high recurrence risk and… read more here.
Keywords: cell; non small; tumor microenvironment; small cell ... See more keywords
Differentially Infiltrated Identification of Novel Diagnostic Biomarkers Associated with Immune Infiltration in Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/3934704
Abstract: Background The prognostic value of tumor-infiltrating immune cells has been widely studied in nasopharyngeal carcinoma (NPC). However, the role of tumor-infiltrating immune cells in the diagnosis of NPC has not been fully elucidated. Thus, tumor-infiltrating… read more here.
Keywords: nasopharyngeal carcinoma; network; tumor infiltrating; diagnostic biomarkers ... See more keywords
Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of ESR1-Mutant Breast Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-20-1200
Abstract: Targetable alterations in MBC, including AR, CHI3L1, and ISG, arise following estrogen-deprivation, and ER-mutant metastases may respond to immunotherapies due to elevated PD-L1+ macrophages. Mutations in ESR1 that confer constitutive estrogen receptor alpha (ER) activity… read more here.
Keywords: steroid hormone; cancer; receptor; breast cancer ... See more keywords
Abstract 5633: Analysis of the immune microenvironment and tumor-infiltrating immune cells across different solid tumors by combined spatial transcriptomics and proteomics
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5633
Abstract: With the advent of immunotherapies such as immune checkpoint inhibitors and CAR T cells, the interest in the tumor microenvironment and tumor-infiltrating lymphocytes (TILs) cells has increased in recent years as these play a critical… read more here.
Keywords: tumor infiltrating; analysis; microenvironment tumor; immune cells ... See more keywords
Abstract P6-06-06: Immunogenomics approach elucidating clinical significance of DNA repair genes and tumor infiltrating immune cells in breast cancer
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DOI: 10.1158/1538-7445.sabcs17-p6-06-06
Abstract: Backgrounds: Evading the immune system is one of the Hallmarks of Cancer. Indeed, tumor infiltrating immune cells has been shown to play critical roles in suppression of cancer progression. Genetic aberration of DNA repair genes… read more here.
Keywords: dna repair; breast cancer; infiltrating immune; cancer ... See more keywords
Infiltrating immune cells in prostate cancer tissue after androgen deprivation and radiotherapy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/03946320231158025
Abstract: Objectives Androgen deprivation therapy (ADT) has long been a cornerstone in treatment of advanced prostate cancer (PCa), and is known to improve the results of radiotherapy (RT) for high-risk disease. The purpose of our study… read more here.
Keywords: infiltration; prostate cancer; androgen deprivation; immune cells ... See more keywords