Association Between Metastatic Melanoma Response to Checkpoint Inhibitor Therapy and Tumor-Infiltrating Lymphocyte Classification on Primary Cutaneous Melanoma Biopsies.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4959
Abstract: This cohort study examines the association between tumor-infiltrating lymphocyte classification and disease progression among patients with metastatic primary cutaneous melanoma receiving checkpoint inhibitor therapy. read more here.
Keywords: tumor infiltrating; melanoma; primary cutaneous; cutaneous melanoma ... See more keywords
Tumor-infiltrating lymphocyte therapy for lung cancer and its future paradigms
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2022.2072206
Abstract: ABSTRACT Introduction Lung cancer is the leading cause of cancer death, with an estimated 1.8 million deaths contributing to this cancer in 2020. Despite advances in treatment options and various approaches being attempted, the survival… read more here.
Keywords: lung cancer; cancer; tumor infiltrating; therapy ... See more keywords
Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies
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DOI: 10.1080/2162402x.2021.1959101
Abstract: ABSTRACT Adoptive transfer of tumor-infiltrating lymphocytes (TIL) elicits the regression of metastatic malignancies, yet a low proportion of patients achieve complete durable responses. The high incidence of relapse in these patients highlights the need to… read more here.
Keywords: tumor infiltrating; til; tumor; modeling vivo ... See more keywords
A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus–associated Epithelial Cancers
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DOI: 10.1158/1078-0432.ccr-18-2722
Abstract: Purpose: Cellular therapy is an emerging cancer treatment modality, but its application to epithelial cancers has been limited. This clinical trial evaluated tumor-infiltrating lymphocyte (TIL) therapy for the treatment of patients with metastatic human papillomavirus… read more here.
Keywords: therapy; infiltrating lymphocyte; epithelial cancers; tumor infiltrating ... See more keywords
Glucocorticoids Mediate Faulty Tumor-Infiltrating Lymphocyte Function.
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DOI: 10.1158/2159-8290.cd-rw2020-140
Abstract: Glucocorticoid signaling promoted a dysfunctional phenotype for tumor-infiltrating CD8+ T cells. read more here.
Keywords: faulty tumor; tumor infiltrating; glucocorticoids mediate; tumor ... See more keywords