Assessing the Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Melanoma Using Pathologic Features Identified by Natural Language Processing
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.26337
Abstract: Key Points Question Are tumor-infiltrating lymphocytes (TILs) an independent prognostic factor for overall survival among patients with primary cutaneous melanoma? Findings This cohort study identified clinical and histopathologic characteristics of 14 436 patients with cutaneous melanoma… read more here.
Keywords: infiltrating lymphocytes; natural language; tumor infiltrating; melanoma using ... See more keywords
The landscape of immune microenvironment in lung adenocarcinoma and squamous cell carcinoma based on PD‐L1 expression and tumor‐infiltrating lymphocytes
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2580
Abstract: The aim of this study was to investigate the tumor microenvironment immune types (TMIT) based on tumor cell programmed cell death ligand 1 (PD‐L1) expression and tumor‐infiltrating lymphocytes (TILs) distribution and whether distinct TMIT subtypes… read more here.
Keywords: lung adenocarcinoma; infiltrating lymphocytes; expression tumor; tumor infiltrating ... See more keywords
Is the presence of tumor‐infiltrating lymphocytes predictive of outcomes in patients with melanoma?
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DOI: 10.1002/cncr.34013
Abstract: The significance of tumor‐infiltrating lymphocytes (TILs) in melanoma is debated. This article presents a multicenter, retrospective study assessing the predictive and prognostic value of TILs. read more here.
Keywords: tumor infiltrating; infiltrating lymphocytes; predictive outcomes; lymphocytes predictive ... See more keywords
Tumor‐infiltrating lymphocytes in breast FNA biopsy cytology: A predictor of tumor‐infiltrating lymphocytes in histologic evaluation
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DOI: 10.1002/cncy.22551
Abstract: Tumor‐infiltrating lymphocytes (TILs) are associated with various clinicopathological features. Using cytologic specimens for assessing TILs remains to be established. This retrospective study aimed to establish a practical method to assess TILs in cytologic samples. read more here.
Keywords: lymphocytes breast; tumor infiltrating; infiltrating lymphocytes; cytology ... See more keywords
In vitro 4-1BB stimulation promotes expansion of CD8+ tumor-infiltrating lymphocytes from various sarcoma subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02568-x
Abstract: Tumor-specific tumor-infiltrating lymphocytes (TILs) can be in vitro expanded and have the ability to induce complete and durable tumor regression in some patients with melanoma following adoptive cell therapy (ACT). In this preclinical study, we… read more here.
Keywords: infiltrating lymphocytes; expansion; stimulation; tumor infiltrating ... See more keywords
Fingolimod and tumor-infiltrating lymphocytes in checkpoint-inhibitor treated cancer patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02693-7
Abstract: Immune checkpoint inhibitors (ICIs) are emerging as the new standard of care for treating various metastatic cancers. It is known that effective anti-tumor immune responses are associated with a stronger presence of tumor-infiltrating lymphocytes (TILs)… read more here.
Keywords: infiltrating lymphocytes; fingolimod; tumor infiltrating; cancer ... See more keywords
Usefulness of imaging findings in predicting tumor-infiltrating lymphocytes in patients with breast cancer
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DOI: 10.1007/s00330-019-06516-x
Abstract: Objectives Tumor-infiltrating lymphocytes (TILs) have been determined as a new prognostic indicator of immunotherapy response in breast cancer (BC). The aim of this study is to investigate the effectiveness of imaging features in predicting the… read more here.
Keywords: stil levels; infiltrating lymphocytes; imaging findings; stil ... See more keywords
Preoperative lymphocyte/C-reactive protein ratio and its correlation with CD8+ tumor-infiltrating lymphocytes as a predictor of prognosis after resection of intrahepatic cholangiocarcinoma
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DOI: 10.1007/s00595-021-02295-5
Abstract: To clarify whether the preoperative lymphocyte/C-reactive protein (CRP) ratio (LCR) is a prognostic factor for patients with intrahepatic cholangiocarcinoma (IHCC), and investigate its mechanism via tumor-infiltrating lymphocytes. The subjects of this retrospective study were 42… read more here.
Keywords: preoperative lymphocyte; infiltrating lymphocytes; reactive protein; tumor infiltrating ... See more keywords
Tumor-infiltrating lymphocytes (TILs) in ER+/HER2− breast cancer
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DOI: 10.1007/s10549-020-05771-7
Abstract: Purpose The prognostic role of tumor-infiltrating lymphocytes (TILs) in ER+/HER2− breast cancer (BC) is debated. We evaluated the association of TILs and clinico-pathological features with distant disease-free survival (DDFS) in patients with ER+/HER2− BC treated… read more here.
Keywords: tumor infiltrating; tils her2; infiltrating lymphocytes; breast cancer ... See more keywords
Tumor-infiltrating lymphocytes in breast cancer according to tumor subtype: Current state of the art.
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DOI: 10.1016/j.breast.2017.07.005
Abstract: The recent success of the immune checkpoint blockade in cancer immunotherapy has modified the treatment algorithms in a variety of aggressive neoplastic diseases. Nevertheless, optimal selection of ideal candidates to these drugs remains a challenge.… read more here.
Keywords: infiltrating lymphocytes; breast cancer; tumor infiltrating; cancer ... See more keywords
The prognostic significance of tumor‐infiltrating lymphocytes for primary melanoma varies by sex
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2018.02.066
Abstract: Background The immune response to melanoma is manifested locally by tumor‐infiltrating lymphocytes (TILs). Men and women are known to have varying patterns of immunity, yet sex‐specific prognostic implications of TILs have not been explored. Methods… read more here.
Keywords: melanoma; sln positivity; infiltrating lymphocytes; tumor infiltrating ... See more keywords