Independent prognostic impact of tumour‐infiltrating macrophages in early‐stage Hodgkin's lymphoma
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DOI: 10.1002/hon.2295
Abstract: Although patients with early‐stage Hodgkin's lymphoma have a high rate of cure, a portion of these are resistant to or relapse after standard treatment. Current prognostic criteria based on clinical and laboratory parameters at diagnosis… read more here.
Keywords: stage hodgkin; infiltrating macrophages; hodgkin lymphoma; early stage ... See more keywords
Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage
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DOI: 10.1038/s41467-019-13894-9
Abstract: DNA damage and metabolic disorders are intimately linked with premature disease onset but the underlying mechanisms remain poorly understood. Here, we show that persistent DNA damage accumulation in tissue-infiltrating macrophages carrying an ERCC1-XPF DNA repair… read more here.
Keywords: dna damage; infiltrating macrophages; tissue infiltrating; damage ... See more keywords
Complement Components Are Expressed by Infiltrating Macrophages/Activated Microglia Early Following Viral Infection.
Sign Up to like & getrecommendations! Published in 2017 at "Viral immunology"
DOI: 10.1089/vim.2016.0175
Abstract: The individual innate immune components, interleukin-6 and complement component C3, play a role in the development of acute seizures in the Theiler's murine encephalomyelitis virus-induced seizure model. We examined the mRNA expression of various other… read more here.
Keywords: complement; macrophages activated; activated microglia; components expressed ... See more keywords
Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma.
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DOI: 10.1158/0008-5472.can-16-2310
Abstract: In glioblastoma (GBM), tumor-associated macrophages (TAM) represent up to one half of the cells of the tumor mass, including both infiltrating macrophages and resident brain microglia. In an effort to delineate the temporal and spatial… read more here.
Keywords: tumor associated; cellular molecular; associated macrophages; molecular identity ... See more keywords
The Eclectic Nature of Glioma-Infiltrating Macrophages and Microglia
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DOI: 10.3390/ijms222413382
Abstract: Glioblastomas (GBMs) are complex ecosystems composed of highly multifaceted tumor and myeloid cells capable of responding to different environmental pressures, including therapies. Recent studies have uncovered the diverse phenotypical identities of brain-populating myeloid cells. Differences… read more here.
Keywords: eclectic nature; myeloid cells; nature glioma; infiltrating macrophages ... See more keywords