Phenotypic and Functional Properties of Tumor-Infiltrating Regulatory T Cells
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/5458178
Abstract: Regulatory T (Treg) cells maintain immune homeostasis by suppressing excessive immune responses. Treg cells induce tolerance against self- and foreign antigens, thus preventing autoimmunity, allergy, graft rejection, and fetus rejection during pregnancy. However, Treg cells… read more here.
Keywords: functional properties; treg cells; properties tumor; tumor infiltrating ... See more keywords
Conversion of CCL18-recruited naïve CD4+ T cells to tumor-infiltrating regulatory T cells in breast cancer and suppression of antitumor immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.7_suppl.114
Abstract: 114Background: Tumor-infiltrating regulatory T cells (Tregs) play a central role in tumor immunosuppression. However, it remains unclear whether they are directly recruited from peripheral blood or converted from infiltrating naive T cells. Methods: We use… read more here.
Keywords: cd4 cells; regulatory cells; breast cancer; tumor infiltrating ... See more keywords