Mobilization of CD4+ T lymphocytes in inflamed mucosa reduces pain in colitis mice: toward a vaccinal strategy to alleviate inflammatory visceral pain
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DOI: 10.1097/j.pain.0000000000001103
Abstract: Abstract T lymphocytes play a pivotal role in endogenous regulation of inflammatory visceral pain. The analgesic activity of T lymphocytes is dependent on their production of opioids, a property acquired on antigen activation. Accordingly, we… read more here.
Keywords: visceral pain; mice; inflamed mucosa; inflammatory visceral ... See more keywords
Inverse and Concordant Mucosal Pathway Gene Expressions in Inflamed and Non-Inflamed Ulcerative Colitis Patients: Potential Relevance to Aetiology and Pathogenesis
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DOI: 10.3390/ijms23136944
Abstract: Ulcerative colitis (UC) arises from a complex interplay between host and environmental factors, but with a largely unsolved pathophysiology. The pathophysiology was outlined by RNA-sequencing of mucosal biopsies from non-inflamed and inflamed colon of UC… read more here.
Keywords: inflamed mucosa; inflamed non; ulcerative colitis; gene ... See more keywords