Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease.
Sign Up to like & getrecommendations! Published in 2020 at "European heart journal"
DOI: 10.1093/eurheartj/ehz961
Abstract: The ongoing worldwide increase in life expectancy portends a rising prevalence of age-related cardiovascular (CV) diseases in the coming decades that demands a deeper understanding of their molecular mechanisms. Inflammation has recently emerged as an… read more here.
Keywords: age; inflammation; disease; inflamm ageing ... See more keywords
Adiponectin receptor agonist AdipoRon blocks skin inflamm-ageing by regulating mitochondrial dynamics.
Sign Up to like & getrecommendations! Published in 2021 at "Cell proliferation"
DOI: 10.1111/cpr.13155
Abstract: INTRODUCTION Skin is susceptible to senescence-associated secretory phenotype (SASP) and inflamm-ageing partly owing to the degeneration of mitochondria. AdipoRon (AR) has protective effects on mitochondria in metabolic diseases such as diabetes. We explored the role… read more here.
Keywords: used detect; aged skin; skin inflamm; inflamm ageing ... See more keywords
IL-1 Mediates Microbiome-Induced Inflamm-Ageing of Hematopoietic Stem Cells in Mice.
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2021011570
Abstract: Ageing is associated with impaired hematopoietic and immune function. This is caused in part by decreased hematopoietic stem cell (HSC) population fitness and an increased myeloid differentiation bias. The reasons for this aging-associated HSC impairment… read more here.
Keywords: wild type; hematopoietic stem; mice; inflamm ageing ... See more keywords