AIM2 Inflammasome Assembly and Signaling.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-9367-9_7
Abstract: AIM2 (absent in melanoma 2) is a cytoplasmic sensor of double-stranded DNA from pathogens or damaged cellular organelles. It recruits ASC (apoptosis-associated specklike protein containing a CARD) and caspase-1 to form the AIM2 inflammasome, activate… read more here.
Keywords: caspase; aim2 inflammasome; assembly signaling; assembly ... See more keywords
POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912069
Abstract: Canonical inflammasomes are innate immune protein scaffolds that enable the activation of inflammatory caspase-1, and subsequently the processing and release of interleukin (IL)-1β, IL-18, and danger signals, as well as the induction of pyroptotic cell… read more here.
Keywords: msu crystal; inflammasome assembly; inflammasome activation; pop1 ... See more keywords