NLRP3 Inflammasome Expression and Signaling in Human Diabetic Wounds and in High Glucose Induced Macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Diabetes Research"
DOI: 10.1155/2017/5281358
Abstract: Introduction. To investigate the contribution and mechanism of NLRP3 inflammasome expression in human wounds in diabetes mellitus and in high glucose induced macrophages. Methods. In the present study, we compared the expression of NLRP3 inflammasome… read more here.
Keywords: inflammasome expression; induced macrophages; high glucose; expression ... See more keywords
Polydatin reduces cardiotoxicity of tyrosine kinase inhibitor sunitinib by decreasing pro-oxidative stress, pro-inflammatory cytokines and NLRP3 inflammasome expression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e15065
Abstract: e15065 Background: : Polydatin has anticancer and anti-inflammatory properties, however no studies investigated on its putative cardioprotective effects against anticancer therapies. Sunitinib, a recently-approved, multi-targeted tyrosine kinases inhibitor, prolongs survival in patients with metastatic renal… read more here.
Keywords: inflammatory; pro inflammatory; nlrp3 inflammasome; polydatin ... See more keywords
Inflammasome expression is higher in ovarian tumors than in normal ovary
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0227081
Abstract: Chronic inflammation fundamentally influences cancer risk and development. A mechanism of chronic inflammation is the formation of inflammasome complexes which results in the sustained secretion of the pro-inflammatory cytokines IL1β and IL18. Inflammasome expression and… read more here.
Keywords: ovarian tumors; ovca; caspase; inflammasome expression ... See more keywords