The NLRP3 inflammasome: Mechanism of action, role in disease and therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2020.100889
Abstract: NLRP3 is the best characterized cytosolic nod-like pattern recognition receptor which can detect microbial motifs, endogenous danger and stress signals. Activation of NLRP3 leads to the formation of a cytosolic multiprotein signaling complex called the… read more here.
Keywords: inflammasome mechanism; mechanism; nlrp3 inflammasome; action role ... See more keywords