Application of advanced microscopic methods to study the interaction of carboxylated fluorescent nanodiamonds with membrane structures in THP-1 cells: Activation of inflammasome NLRP3 as the result of lysosome destabilisation.
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DOI: 10.1021/acs.molpharmaceut.9b00225
Abstract: Nanodiamonds (ND), especially fluorescent nanodiamonds represent potentially applicable drugs and probes carriers for in vitro/in vivo applications. The main purpose of this study was to relate physical-chemical properties of carboxylated ND to their intracellular distribution,… read more here.
Keywords: microscopic methods; cells activation; fluorescent nanodiamonds; inflammasome nlrp3 ... See more keywords