Blocking the inflammasome: a novel approach to treat uveitis.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.06.017
Abstract: Uveitis is a complex ocular inflammatory disease often accompanied by bacterial or viral infections (infectious uveitis) or underlying autoimmune diseases (non-infectious uveitis). Treatment of the underlying infection along with corticosteroid-mediated suppression of acute inflammation usually… read more here.
Keywords: inflammasome novel; infectious uveitis; blocking inflammasome; disease ... See more keywords
The NLRP3 Inflammasome as a Novel Therapeutic Target for Cardiac Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s370483
Abstract: Abstract Cardiac fibrosis often has adverse cardiovascular effects, including heart failure, sudden death, and malignant arrhythmias. However, there is no targeted therapy for cardiac fibrosis. Inflammation is known to play a crucial role in the… read more here.
Keywords: cardiac fibrosis; novel therapeutic; inflammasome novel; fibrosis ... See more keywords